Briquilimab is under clinical development by Jasper Therapeutics and currently in Phase II for Severe Combined Immune Deficiency (SCID). According to GlobalData, Phase II drugs for Severe Combined Immune Deficiency (SCID) have a 100% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how Briquilimab’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Briquilimab (AMG-191) is under development for the treatment of fanconi anemia, myelodysplastic syndrome, severe combined immunodeficiency, acute myeloid leukemia, sickle cell disease, chronic granulomatous disease (CGD) and Gaucher disease type 1. The drug candidate acts by targeting stem cell growth factor receptor Kit. It is a humanized anti-c-Kit monoclonal antibody. It is administered through intravenous route. It was also under development for the treatment of inflammatory diseases such as idiopathic pulmonary fibrosis (IPF).
Jasper Therapeutics overview
Jasper Therapeutics focuses on development and commercialization of hematopoietic stem cell transplants. It develops and commercializes stem cell engineering for expanded use of stem cell transplantation. The company pipeline products are JSP191 is in clinical development that clears hematopoietic stem cells from bone marrow. It also engineered hematopoietic stem cells(eHSCs) platform to address the limitations of transplant grafts and unlock the potential of stem cells. Jasper Therapeutics is headquartered in ReedWood, California, The US.
For a complete picture of Briquilimab’s drug-specific PTSR and LoA scores, buy the report here.