CBP-201 is under clinical development by Suzhou Connect Biopharmaceuticals and currently in Phase I for Eosinophilic Esophagitis. According to GlobalData, Phase I drugs for Eosinophilic Esophagitis have a 90% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how CBP-201’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

CBP-201 overview

CBP-201 is under development for the treatment of allergic inflammation such as asthma, atopic dermatitis, food allergy, eosinophilic esophagitis, chronic obstructive pulmonary disease (COPD). The drug candidate is a human monoclonal IgG4 monoclonal antibody that binds to IL-4R alpha. It is administered as subcutaneous or intravenous injection. It was also under development for nasal polyps.

It was also under development for the treatment of chronic rhinosinusitis.

Suzhou Connect Biopharmaceuticals overview

Suzhou Connect Biopharmaceuticals (Connect Biopharmaceuticals) discovers and develops next-generation immune modulators for the treatment of autoimmune diseases and inflammation. The company’s pipeline Product portfolio includes CBP-307 is an orally-active small molecule used for the treatment of ulcerative colitis (UC) and Crohn’s disease (CD); CBP-201 is an antibody for asthma and atopic dermatitis; and CBP-174 is a small molecule inhibitor for the treatment of chronic skin inflammation. It utilizes T cell modulation technology platform for developing their products. Connect Biopharmaceuticals serves in the therapeutic areas of inflammatory bowel disease, psoriasis, multiple sclerosis and other autoimmune diseases. The company seeks to collaborate with pharmaceutical companies to develop and commercialize their products both inside and outside China. Connect Biopharmaceuticals is headquartered in Taicang, Jiangsu, China.

For a complete picture of CBP-201’s drug-specific PTSR and LoA scores, buy the report here.

GlobalData

GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in its clinical pathway (PTSR), as well as how likely the drug will be approved (LoA). This is based on a proprietary algorithm built from the drugs’ sales forecast, regulatory milestones, cost forecasts, WACC rate and other proprietary data sources found on GlobalData’s Pharmaceutical Intelligence Center.