Chiesi Farmaceutici has been granted a patent for a process to prepare compounds with PDE4 inhibitory activity, suitable for inhalation in pharmaceutical compositions for respiratory disease treatment. The patent also covers solvates and crystal forms of the compound. GlobalData’s report on Chiesi Farmaceutici gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Chiesi Farmaceutici, Inhalation devices was a key innovation area identified from patents. Chiesi Farmaceutici's grant share as of May 2024 was 49%. Grant share is based on the ratio of number of grants to total number of patents.
Pharmaceutical formulation with pde4 inhibitory activity for inhalation
A recently granted patent (Publication Number: US11981639B2) discloses a pharmaceutical formulation that includes a crystal form of a compound of formula (I). The formulation is designed for inhalation or intranasal administration and can also be in the form of a capsule or dry powder suitable for inhalation. This innovative formulation aims to treat inflammatory or obstructive respiratory diseases effectively.
Moreover, the patent also covers a process for preparing the crystal form of the compound of formula (I), ensuring that the total amount of impurities in the crystal is minimal, ranging from less than 5% w/w to as low as 0.5% w/w. The process involves specific steps such as heating a suspension of the compound in ethyl acetate/heptane or isopropyl acetate under controlled conditions. The resulting crystal form, with a high percentage of crystallinity exceeding 90% w/w, is crucial for the efficacy of the pharmaceutical formulation. This crystal form can be utilized in the treatment of inflammatory or obstructive respiratory diseases like asthma or chronic obstructive pulmonary disease, offering a promising therapeutic approach for patients in need.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
