CHM-2101 is under clinical development by Chimeric Therapeutics and currently in Phase II for Gastric Cancer. According to GlobalData, Phase II drugs for Gastric Cancer have a 28% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how CHM-2101’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

CHM-2101 overview

CHM-2101 is under development for the treatment of neuroendocrine tumors, colorectal cancer, pancreatic cancer, rectal cancer and gastric cancer. The therapeutic candidate comprises of autologous T cells genetically manipulated to express chimeric antigen receptor (CAR) targeting cells expressing Cadherin-17 (CDH17) antigen. It is administered through intravenous route.

Chimeric Therapeutics overview

Chimeric Therapeutics, a subsidiary of Cell and Gene Therapy Catapult, is a clinical-stage cell therapy company that discovers and develops therapies for the treatment of cancer. The company focuses on the development of cell-based allogenic and autologous therapies. It is investigating CHM1301 and CHM 2301 programs against solid tumors; CHM 0301, to treat blood cancer and CHM 0201, for hematological malignancies disorder and solid tumors. Chimeric Therapeutics is also developing chimeric antigen receptor (CAR) T cell-based therapies such as CHM 1101 program for the treatment of glioblastoma, melanoma and colorectal cancer and CHM 2101 against Neuroendocrine cancer. Chimeric Therapeutics is headquartered in Carlton, Victoria, Australia.

For a complete picture of CHM-2101’s drug-specific PTSR and LoA scores, buy the report here.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.