Cipla has been granted a patent for a long-term storage stable multi-dose pharmaceutical liquid formulation containing pemetrexed for lung cancer treatment. The formulation includes specific ingredients and must meet purity standards after six months of storage. GlobalData’s report on Cipla gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Cipla, Peptide pharmacophores was a key innovation area identified from patents. Cipla's grant share as of April 2024 was 39%. Grant share is based on the ratio of number of grants to total number of patents.
A recently granted patent (Publication Number: US11931362B2) discloses a long-term storage multi-dose pharmaceutical liquid formulation containing pemetrexed or its salt, an antioxidant, a preservative, and a buffering agent. The formulation, stored for six months at specified conditions, must contain no more than 1.0% total impurity. The antioxidant options include monothioglycerol, L-cysteine, and others, while preservatives like benzyl alcohol or m-cresol are included in specific amounts. The buffering agent, such as sodium citrate, is crucial for stability and must be present within a defined range.
Moreover, the patent details methods for producing the formulation and its application in treating malignant pleural mesothelioma or non-squamous, non-small cell lung cancer. The formulation can be combined with cisplatin or carboplatin with pembrolizumab for enhanced therapeutic effects. Additionally, a kit containing the pharmaceutical formulation in vials along with storage and usage instructions is also part of the patent. The formulation's pH, presence of pemetrexed in specific concentrations, and absence of amino acids are highlighted features, making it suitable for parenteral administration and long-term storage.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
