Colchicine is a Small Molecule owned by Takeda Pharmaceutical, and is involved in 19 clinical trials, of which 18 were completed, and 1 is ongoing.
Colchicine disrupts cytoskeletal functions through inhibition of beta-tubulin polymerization into microtubules, and consequently prevents the activation, degranulation, and migration of neutrophils thought to mediate some gout symptoms. Colchicine may interfere with the intracellular assembly of the inflammasome complex present in neutrophils and monocytes that mediates activation of interleukin-1beta.
The revenue for Colchicine is expected to reach a total of $13m through 2025. This change impacts the valuation of this asset and is an important factor to understand the current value of the drug in a clinical process. GlobalData uses proprietary data and analytics to provide a complete picture of this assessment in their Colchicine NPV Report.
Colchicine is currently owned by Takeda Pharmaceutical.
Colchicine Overview
Colchicine (Colcrys/ Cocichimil) is an alkaloid, gout suppressant and tubulin modulator. It is formulated as film-coated tablets, tablets for oral route of administration. Colchicine is indicated for the prophylaxis and treatment of acute gout flares, it is also indicated in adults and children 4 years or older for the treatment of familial Mediterranean fever (FMF). It was also under development for the treatment of Behcet's disease.
Takeda Pharmaceutical Overview
Takeda Pharmaceutical (Takeda) is a research-based pharmaceutical company which focuses on the discovery, development, manufacturing, marketing, commercialization, import and export of pharmaceutical drugs. The company offers products in the areas of rare diseases, gastrointestinal, oncology, neuroscience, vaccines, and plasma-derived therapies. Takeda has facilities in Japan, Argentina, Brazil, Mexico, the US, Denmark, Norway, Europe, Poland, Russia, Spain, Switzerland, China and India, Canada among others. It markets products directly and through a network of wholesale distributors, retail chains and other purchasing groups worldwide. Takeda has partnership with academic institutions, small biotech, and large pharmaceutical companies. It has presence in the Americas, Europe, and Asia, among others. Takeda is headquartered in Tokyo, Japan.
The company reported revenues of (Yen) JPY3,569,006 million for the fiscal year ended March 2022 (FY2022), an increase of 11.6% over FY2021. In FY2022, the company’s operating margin was 12.5%, compared to an operating margin of 18.8% in FY2021. In FY2022, the company recorded a net margin of 6.4%, compared to a net margin of 11.8% in FY2021.
The company reported revenues of JPY1,002,307 million for the second quarter ended September 2022, an increase of 3.1% over the previous quarter.
Quick View – Colchicine
Report Segments |
|
Drug Name |
|
Administration Pathway |
|
Therapeutic Areas |
|
Key Companies |
|
Highest Development Stage |
|