(Cycloserine + lurasidone hydrochloride) is under clinical development by NRX Pharmaceuticals and currently in Phase III for Bipolar Disorder (Manic Depression). According to GlobalData, Phase III drugs for Bipolar Disorder (Manic Depression) have a 68% phase transition success rate (PTSR) indication benchmark for progressing into Pre-Registration. GlobalData’s report assesses how (Cycloserine + lurasidone hydrochloride)’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

(Cycloserine + lurasidone hydrochloride) overview

D-Cycloserine in a fixed dose combination with lurasidone hydrochloride (NRX-101) is under development for the treatment of acute suicidal ideation/behaviour (ASIB) associated with bipolar depression, post traumatic stress disorder, complicated urinary tract infections including pyelonephritis and chronic nociceptive pain. It is administered through oral route as a capsule. D-Cycloserine acts by targeting NMDA receptor and lurasidone hydrochloride targets 5HT2A receptor.

NRX Pharmaceuticals overview

NRX Pharmaceuticals formerly Big Rock Partners Acquisition is a pharmaceutical company developing novel therapies for respiratory disorders. The company is headquartered in Wilmington, Delaware, the US.

For a complete picture of (Cycloserine + lurasidone hydrochloride)’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 20 February 2024

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GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.