The Cytotoxic T Lymphocyte Protein 4 pipeline drugs market research report outlays comprehensive information on the Cytotoxic T Lymphocyte Protein 4 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Cytotoxic T Lymphocyte Protein 4 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Oncology, Immunology, Genetic Disorders, and Non Malignant Disorders which include the indications Solid Tumor, Non-Small Cell Lung Cancer, Rheumatoid Arthritis, Autoimmune Disorders, Neurofibromatoses Type I (Von Recklinghausen’s Disease), and Inflammatory Myofibroblastic Tumor (IMT). It also reviews key players involved in Cytotoxic T Lymphocyte Protein 4 targeted therapeutics development with respective active and dormant or discontinued products.
The Cytotoxic T Lymphocyte Protein 4 pipeline targets constitutes close to 83 molecules. Out of which, approximately 82 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Pre-Registration, Phase III, Phase II, Phase I, IND/ CTA Filed, Preclinical, and Discovery stages are 3, 9, 18, 16, 3, 29, and 4 respectively. Similarly, the universities portfolio in Preclinical comprises 1 molecule.
Cytotoxic T Lymphocyte Protein 4 overview
CTLA4 also known as CD152 is a protein receptor found on the surface of T cells. It functions as an immune checkpoint and down regulates the immune system. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory co-receptor CD28. Inhibition of receptor acts as a major negative regulator of T-cell responses.
For a complete picture of Cytotoxic T Lymphocyte Protein 4’s drug pipeline, buy the report here.
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