Daiichi Sankyo has patented a novel method for producing diarylpyridine derivatives without using palladium or high-temperature reactions. The method involves synthesizing pyridine rings from iminium salts and cyano compounds under mild conditions. GlobalData’s report on Daiichi Sankyo gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Daiichi Sankyo, Cancer treatment biomarkers was a key innovation area identified from patents. Daiichi Sankyo's grant share as of May 2024 was 44%. Grant share is based on the ratio of number of grants to total number of patents.

Method for producing diarylpyridine derivatives using novel synthesis method

Source: United States Patent and Trademark Office (USPTO). Credit: Daiichi Sankyo Co Ltd

A recently granted patent (Publication Number: US11999724B2) discloses a production method involving a series of steps for reacting specific chemical compounds represented by various formulas. The method includes utilizing chlorinating agents like oxalyl chloride, bases such as 2,6-lutidine, and reacting compounds with different reagents to obtain desired compounds represented by specific formulas. For instance, the method involves reacting compounds with Wittig reagents, benzylamine, and hydrogen in the presence of a palladium on carbon catalyst to achieve the desired end products.

Furthermore, the patent outlines additional steps such as condensing specific compounds with others and utilizing different salts and solvents in the process. The method described in the patent aims to efficiently produce compounds represented by various formulas by following a precise sequence of reactions and utilizing specific reagents and catalysts. The patent provides a detailed guide for carrying out the production method, ensuring the reproducibility and reliability of the process for obtaining the desired chemical compounds.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies