Daprodustat is under clinical development by GSK and currently in Phase III for Anemia in Chronic Kidney Disease (Renal Anemia). According to GlobalData, Phase III drugs for Anemia in Chronic Kidney Disease (Renal Anemia) have a 63% phase transition success rate (PTSR) indication benchmark for progressing into Pre-Registration. GlobalData’s report assesses how Daprodustat’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Daprodustat overview
Daprodusta (Duvroq, Jesduvroq) is an anti anemic agent. It is formulated as film coated tablets for oral route of administration. Duvroq indicated for the treatment of anaemia due to chronic kidney disease in adult patients not on dialysis and on dialysis. Jesduvroq is indicated for the treatment of anemia due to chronic kidney disease (CKD) in adults who have been receiving dialysis for at least four months.
The drug candidate can be applied topically as an ointment. It is a prolyl hydroxylase inhibitor.The drug candidate was also under development for the treatment of peripheral arterial disease (PAD)/peripheral vascular disease (PVD), ischemic events in patients undergoing thoracic aortic aneurysm repair, diabetic foot ulcer, wounds and tendon injuries.
GSK overview
GSK is a healthcare company that focuses on developing, manufacturing and commercializing general medicines, specialty medicines and vaccines. It offers drugs for the treatment of diseases such as HIV, respiratory, cancer, immuno-inflammation, anti-viral, central nervous system (CNS), metabolic, cardiovascular, and urogenital, anti-bacterial, dermatology and rare diseases. The company also offers over-the-counter (OTC) products for pain relief, oral health, nutrition, skin health and gastrointestinal diseases. GSK’s vaccine portfolio covers various diseases including hepatitis, diphtheria, tetanus, whooping cough, rotavirus and HPV infections, measles and bacterial meningitis, among others. The company sells its products through wholesalers, pharmacies, hospitals, physicians and other groups worldwide. GSK is headquartered in Brentford, Middlesex, the UK.
For a complete picture of Daprodustat’s drug-specific PTSR and LoA scores, buy the report here.
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