Doravirine is a Small Molecule owned by Merck & Co, and is involved in 54 clinical trials, of which 41 were completed, 9 are ongoing, and 4 are planned.
Doravirine (MK-1439) acts as an antiretroviral agent. It is an non-nucleoside reverse transcriptase inhibitor (NNRTI). The enzyme reverse transcriptase is essential in the replication of HIV. Non-nucleoside reverse transcriptase inhibitors or NNRTI's also interferes with reverse transcriptase. NNRTI's prevent the human immunodeficiency virus (HIV) from multiplying.
The revenue for Doravirine is expected to reach a total of $2.9bn through 2038. This change impacts the valuation of this asset and is an important factor to understand the current value of the drug in a clinical process. View the complete picture with the Doravirine NPV Report.
Doravirine is originated and owned by Merck & Co.
Doravirine (Pifeltro/Pipeltro) is s a diarylpyrimidine derivative, acts as an antiretroviral agent. It is formulated as film coated tablets and tablets for oral route of administration. Pifeltro is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection with no prior antiretroviral treatment history in adults. Pifeltro is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and pediatric patients weighing at least 35 kg with no prior antiretroviral treatment history or to replace the current antiretroviral regimen in those who are virologically suppressed (HIV-1 RNA less than 50 copies per mL) on a stable antiretroviral regimen with no history of treatment failure and no known substitutions associated with resistance to doravirine.
Merck & Co Overview
Merck & Co (Merck) is a biopharmaceutical company focused on the discovery, development, manufacturing and marketing of prescription medicines, biologic therapies, vaccines and animal health products. It offers prescription products for therapy areas related to cardiovascular, cancer, immune disorders, infectious, respiratory and women’s diseases, and diabetes. The company provides animal health products such as vaccines, poultry products, livestock products and aquaculture products. Merck sells medicines to drug wholesalers, retailers, hospitals, government agencies and managed health care providers; and animal health products to veterinarians, distributors and animal producers. The company and its subsidiaries operate in the Americas, Europe, the Middle East, Africa, Asia Pacific, and Latin America. Merck is known as MSD outside the US and Canada and is headquartered in Kenilworth, New Jersey, the US.
The company reported revenues of (US Dollars) US$48,704 million for the fiscal year ended December 2021 (FY2021), an increase of 17.3% over FY2020. In FY2021, the company’s operating margin was 25.7%, compared to an operating margin of 12% in FY2020. In FY2021, the company recorded a net margin of 26.8%, compared to a net margin of 17% in FY2020. The company reported revenues of US$14,959 million for the third quarter ended September 2022, an increase of 2.5% over the previous quarter.
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