Enzo Biochem‘s patent involves methods and compositions for detecting and quantifying modified compounds in samples. The process includes isolating compounds that have gained functional groups from those that have not, using specific techniques like precipitation with charged metal ions and solvents. GlobalData’s report on Enzo Biochem gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Enzo Biochem, Cancer treatment biomarkers was a key innovation area identified from patents. Enzo Biochem's grant share as of February 2024 was 57%. Grant share is based on the ratio of number of grants to total number of patents.

Method for detecting enzymes adding functional groups to compounds

Source: United States Patent and Trademark Office (USPTO). Credit: Enzo Biochem Inc

A recently granted patent (Publication Number: US11874281B2) discloses a method for detecting or quantifying an enzyme capable of adding a functional group to a compound in a sample. The method involves providing a compound directly covalently bound to a non-radioactive signaling moiety, a sample suspected of containing the enzyme, a source of the functional group, and means to separate the compound. The mixture is incubated to allow the compound to gain the functional group, which is then isolated by precipitating with a charged metal ion and a solvent. The resolubilized compound is then detected or quantified by the non-radioactive signaling moiety.

Furthermore, the method includes additional steps such as providing a normalizing reagent to promote precipitation, using specific compounds for precipitation and resolubilization, and blocking interfering moieties on the compound. The non-radioactive signaling moiety can be a variety of compounds like fluorescent, phosphorescent, chemiluminescent, chromogenic, chelating, electron dense, magnetic, energy transfer members, intercalating compounds, or combinations thereof. The detection or quantification of the compound can be carried out directly or indirectly, enhancing the versatility and applicability of the method in various enzyme detection scenarios. This patented method offers a comprehensive approach to detecting and quantifying enzymes in samples, providing a valuable tool for research and diagnostic applications in the field.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies