EO-2401 is under clinical development by Enterome Bioscience and currently in Phase II for Recurrent Glioblastoma Multiforme (GBM). According to GlobalData, Phase II drugs for Recurrent Glioblastoma Multiforme (GBM) have a 24% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how EO-2401’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

EO-2401 overview

EO-2401 is under development for the treatment of recuurent glioblastoma multiforme, adrenocortical carcinoma, pheochromocytoma and paraganglioma. The drug candidate is next-generation microbiome-derived vaccines acts by targeting novel antigens named onco-mimics. It is administered through subcutaneous route. It is developed based on quantitative metagenomics and functional metagenomics platform.

Enterome Bioscience overview

Enterome Bioscience (Enterome) is a drug development company which develops medical tests, and companion diagnostics to develop the management of microbiome-related diseases. The company develops medical tests based on its metagenotype technology platform that helps to identify microbiome-based biomarkers and screen for microbiome-derived molecules. It also develops new diagnostic products for patient classification and forecasting treatment response. Enterome provides microbiome-derived molecules as drug candidates. The company develops drugs for treatment of microbiome-related diseases which include metabolic, inflammatory bowel diseases, and central nervous system linked diseases. Enterome is headquartered in Paris, France.

For a complete picture of EO-2401’s drug-specific PTSR and LoA scores, buy the report here.


GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in its clinical pathway (PTSR), as well as how likely the drug will be approved (LoA). This is based on a proprietary algorithm built from the drugs’ sales forecast, regulatory milestones, cost forecasts, WACC rate and other proprietary data sources found on GlobalData’s Pharmaceutical Intelligence Center.