EpiVax has been granted a patent for a method involving T cell epitopes derived from immunoglobulin regions to induce regulatory T-cells for immune suppression. The method includes administering a composition containing specific T-cell epitope polypeptides. GlobalData’s report on EpiVax gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on EpiVax, Peptide pharmacophores was a key innovation area identified from patents. EpiVax's grant share as of January 2024 was 34%. Grant share is based on the ratio of number of grants to total number of patents.

Inducing regulatory t-cells to suppress immune response

Source: United States Patent and Trademark Office (USPTO). Credit: EpiVax Inc

A recently granted patent (Publication Number: US11844826B2) discloses a method for inducing regulatory T-cells to suppress immune responses in a subject. The method involves administering a T-cell epitope composition containing isolated T-cell epitope polypeptides, with at least one polypeptide having a specific amino acid sequence. Additionally, the composition may include other isolated T-cell epitope polypeptides with different amino acid sequences to enhance the immune suppressive effect.

Furthermore, the T-cell epitope composition may also contain antigens and/or allergens in addition to the isolated T-cell epitope polypeptides. The immune suppressive effect can be mediated by natural regulatory T-cells or adaptive regulatory T-cells, and the composition is designed to suppress effector T-cell responses, including cytokine secretion, helper T-cell responses, and B-cell responses. This patent provides a novel approach to modulating immune responses in subjects by targeting specific T-cell epitopes to induce regulatory T-cells for immune suppression.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies