EpiVax has been granted a patent for a method involving T cell epitopes derived from immunoglobulin regions to induce regulatory T-cells for immune suppression. The method includes administering a composition containing specific T-cell epitope polypeptides. GlobalData’s report on EpiVax gives a 360-degree view of the company including its patenting strategy. Buy the report here.
According to GlobalData’s company profile on EpiVax, Peptide pharmacophores was a key innovation area identified from patents. EpiVax's grant share as of January 2024 was 34%. Grant share is based on the ratio of number of grants to total number of patents.
Inducing regulatory t-cells to suppress immune response
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A recently granted patent (Publication Number: US11844826B2) discloses a method for inducing regulatory T-cells to suppress immune responses in a subject. The method involves administering a T-cell epitope composition containing isolated T-cell epitope polypeptides, with at least one polypeptide having a specific amino acid sequence. Additionally, the composition may include other isolated T-cell epitope polypeptides with different amino acid sequences to enhance the immune suppressive effect.
Furthermore, the T-cell epitope composition may also contain antigens and/or allergens in addition to the isolated T-cell epitope polypeptides. The immune suppressive effect can be mediated by natural regulatory T-cells or adaptive regulatory T-cells, and the composition is designed to suppress effector T-cell responses, including cytokine secretion, helper T-cell responses, and B-cell responses. This patent provides a novel approach to modulating immune responses in subjects by targeting specific T-cell epitopes to induce regulatory T-cells for immune suppression.
To know more about GlobalData’s detailed insights on EpiVax, buy the report here.
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