EpiVax has been granted a patent for compositions containing regulatory T cell epitopes, including polypeptides from SEQ NOS: 1-124. The patent also covers methods of producing and using these compositions to induce regulatory T-cells and suppress immune responses in subjects, with specific reference to SEQ ID NO: 7. GlobalData’s report on EpiVax gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on EpiVax, Peptide pharmacophores was a key innovation area identified from patents. EpiVax's grant share as of April 2024 was 34%. Grant share is based on the ratio of number of grants to total number of patents.

Method of inducing regulatory t-cells to suppress immune response

Source: United States Patent and Trademark Office (USPTO). Credit: EpiVax Inc

The granted patent (Publication Number: US11911414B2) discloses a method for inducing regulatory T-cells to suppress immune responses in a subject by administering a T-cell epitope composition. This composition includes one or more isolated T-cell epitope polypeptides, with at least one polypeptide having a specific amino acid sequence. Additionally, the composition may contain other T-cell epitope polypeptides with different amino acid sequences, antigens, and/or allergens to enhance its therapeutic effectiveness.

Furthermore, the method described in the patent can lead to immune suppression mediated by natural regulatory T cells or adaptive regulatory T-cells. It is designed to suppress effector T-cell responses, including cytokine secretion, as well as helper T-cell and B-cell responses. By targeting specific T-cell epitopes, this method offers a novel approach to modulating immune responses in a subject, potentially leading to new treatment options for various conditions where immune dysregulation plays a role.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies