Epoetin alfa is a Recombinant Protein owned by Amgen, and is involved in 68 clinical trials, which were completed.
Epoetin alfa, a glycoprotein containing 165 amino acids is produced by recombinant DNA technology. It contains the identical amino acid sequence of isolated erythropoietin. Erythropoietin which is naturally produced in the body stimulates red blood cell production. Recombinant epoetin has similar biological activity to the endogenous hormone, which induces erythropoiesis by stimulating the division and differentiation of committed erythroid progenitor cells, including burst-forming units–erythroid, colony-forming units–erythroid, erythroblasts, and reticulocytes, in bone marrow. It also induces the release of reticulocytes from the bone marrow into the blood stream, where they mature into erythrocytes.
The revenue for Epoetin alfa is expected to reach a total of $3.3bn through 2038. This change impacts the valuation of this asset and is an important factor to understand the current value of the drug in a clinical process. View the complete picture with the Epoetin alfa NPV Report.
Epoetin alfa Overview
Epoetina Alfa (Epogen, Procrit, Espo, Eprex, Prrex, Hemoprex, Erypo) is a erythropoiesis-stimulating glycoprotein manufactured by recombinant DNA technology. It is formulated as injection solution for intravenous or subcutaneous route of administration. It is indicated for the treatment of anemia due to chronic kidney disease, zidovudine in HIV-infected patients and chemotherapy in patients with cancer. It is also used in reduction of allogeneic red blood cell transfusions in patients undergoing elective, noncardiac, nonvascular surgery and Eprex (epoetin alfa) is indicated for the treatment of symptomatic anaemia in adults with low- or intermediate-1-risk primary myelodysplastic syndromes (MDS) who have low serum erythropoietin.
Johnson & Johnson Overview
Johnson & Johnson (J&J) researches, develops, manufactures, and sells pharmaceutical products, medical devices, and consumer products. The company provides pharmaceuticals for immune diseases, cancer, neurological disorders, infectious, cardiovascular and metabolic diseases; consumer products in oral care, baby care, beauty, over-the-counter (OTC) medicines, women’s health and wound care categories; and medical devices for use in the cardiovascular, orthopaedic, general surgery and vision care fields. J&J distributes pharmaceutical and medical products to retailers, wholesalers, health care professionals and hospitals; and offers consumer products through retail outlets and distributors. The company offers its products in the US; Europe; Asia-Pacific and Africa; and Western Hemisphere (excluding the US). J&J is headquartered in New Brunswick, New Jersey, the US.
The company reported revenues of (US Dollars) US$93,775 million for the fiscal year ended January 2021 (FY2021), an increase of 13.6% over FY2020. In FY2021, the company’s operating margin was 24.3%, compared to an operating margin of 20% in FY2020. In FY2021, the company recorded a net margin of 22.3%, compared to a net margin of 17.8% in FY2020. The company reported revenues of US$23,791 million for the third quarter ended October 2022, a decrease of 1% over the previous quarter.
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