Evazarsen sodium is under clinical development by Ionis Pharmaceuticals and currently in the Phase II in clinical pathway. The characteristics of the clinical trial as well as other attributes related to the drug, regulations, and company play a fundamental role in ensuring the likelihood of transition that the drug moves from its current development stage to next.

According to GlobalData, the latest event to affect Evazarsen sodium’s likelihood of approval (LoA) and phase transition for Resistant Hypertension took place on 11 Dec 2020, which increased the likelihood that the drug progresses to the next phase in its clinical pathway.

GlobalData uses proprietary data and analytics to provide a complete picture of this assessment in their Evazarsen sodium Likelihood of Approval (LoA) and Phase Transition Success Rate (PTSR) Report.

Evazarsen sodium overview

IONIS-AGT-LRx is under development for treatment-resistant hypertension, mild hypertension and heart failure with reduced ejection fraction (systolic heart failure). It is administered through the subcutaneous route. It is an antisense oligonucleotide which acts by targeting angiotensinogen (AGT). It is developed based on ligand conjugation antisense (LICA) technology.

Ionis Pharmaceuticals overview

Ionis Pharmaceuticals (Ionis), formerly ISIS Pharmaceuticals, Inc., focuses on the discovery and development of RNA-targeted drugs. The company develops medicines to treat various diseases including cancer, pulmonary, cardiovascular diseases, neurological and infectious diseases. Its major products include Spinraza for spinal muscular atrophy, Tegsedi for neuropathy and Waylivra for familial chylomicronemia syndrome. Ionis also has a pipeline of products in different phases of clinical trials. It develops products based on its proprietary antisense technology. The company partnered with other pharmaceutical companies to develop a range of products in different therapeutic areas. The company sells its products in North America and Europe. Ionis is headquartered in Carlsbad, California, the US.

Quick View Evazarsen sodium LOA Data

Report Segments
  • Innovator
Drug Name
  • Evazarsen sodium
Administration Pathway
  • Subcutaneous
Therapeutic Areas
  • Cardiovascular
Key Developers
Highest Development Stage
  • Phase II

GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in its clinical pathway (PTSR), as well as how likely the drug will be approved (LoA). This is based on a proprietary algorithm built from the drugs’ sales forecast, regulatory milestones, cost forecasts, WACC rate and other proprietary data sources found on GlobalData’s Pharmaceutical Intelligence Center.