Fenretinide is under clinical development by SciTech Development and currently in Phase I for Peripheral T-Cell Lymphomas (PTCL). According to GlobalData, Phase I drugs for Peripheral T-Cell Lymphomas (PTCL) have a 90% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how Fenretinide’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Fenretinide overview

Fenretinide is under development for the treatment of small-cell lung cancer, t-cell non-Hodgkin's lymphomas (T-Cell NHL) including cutaneous t-cell lymphoma (CTCL) subtypes mycosis fungoides (MF) and sezary Syndrome (SS), non-cutaneous t-cell lymphoma (non-CTCL) subtypes angioimmunoblastic t-cell lymphoma (AITL), anaplastic large cell lymphoma, peripheral t-cell lymphoma (PTCL) and follicular t-cell lymphoma (FTCL). It is developed as nanometer-sized liposomes using vehicle SDV, triglyceride-free drug formulation. The drug candidate is administered through the intravenous route and formulated as suspension. Fenretinide is a synthetic retinoid derivative related to vitamin A (retinol). It was also under development for follicular T-cell lymphoma.

It was also under development for the treatment of coronavirus disease (COVID-19).

SciTech Development overview

SciTech Development (SciTech) is a biopharmaceutical company that has developed a proprietary nano-delivery system (SciTech Delivery Vehicle – SDV) to enable intravenous (IV) delivery of water-insoluble drugs. SciTech is headquartered in Grosse Pointe Farms, Michigan, the US.

For a complete picture of Fenretinide’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 1 April 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.