The Free Fatty Acid Receptor 4 pipeline drugs market research report outlays comprehensive information on the Free Fatty Acid Receptor 4 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Free Fatty Acid Receptor 4 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Metabolic Disorders, and Gastrointestinal which include the indications Type 2 Diabetes, Diabetes, Metabolic Dysfunction-Associated Steatohepatitis (MASH), and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). It also reviews key players involved in Free Fatty Acid Receptor 4 targeted therapeutics development with respective active and dormant or discontinued products.
The Free Fatty Acid Receptor 4 pipeline targets constitutes close to six molecules. Out of which, approximately six molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase I, and Preclinical stages are 1, and 5 respectively.
Free Fatty Acid Receptor 4 overview
Free Fatty Acid Receptor 4 is a G protein-coupled receptor (GPR) encoded by FFAR4 gene. It acts as receptor for medium and long-chain free fatty acids (FFAs). It acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects, particularly in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1-dependent effect, but independent of the G (q)/G (11)-coupled pathway. It mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation. It mediates the taste of fatty acids.
For a complete picture of Free Fatty Acid Receptor 4’s drug pipeline, buy the report here.
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