FS-102 is under clinical development by F-star Therapeutics and currently in Phase I for Gastric Cancer. According to GlobalData, Phase I drugs for Gastric Cancer have a 77% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how FS-102’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
FS-102 is under development for the treatment of solid tumors including HER2+ breast cancer, gastric cancer and gastroesophageal junction adenocarcinoma. It is administered intravenously. The drug candidate is developed based on Fcab (an Fc-domain with antigen binding sites) technology. The antibody targets human epidermal growth factor receptor 2 (HER-2). It was also under development for the treatment of colorectal cancer.
F-star Therapeutics overview
F-star Therapeutics, a subsidiary of invoX Pharma Ltd, is a clinical-stage biopharmaceutical company that develops novel, innovative tetravalent bispecific antibodies for cancer and serious illnesses. The company’s pipeline products include FS118, FS120, FS222 and SB 11285. Its pipeline candidates treat rescuing clinical practice improvement (CPI) treatment failures and improving outcomes in the clinical practice improvement (CPI) naive, improving outcomes in programmed cell death ligand 1 (PD-L1) low tumors, improving CPI and chemotherapy outcomes. F-star Therapeutics partners programs include multiple blood-brain barriers, multiple immuno-oncology, STING inhibitors and multiple next-generation bispecific antibodies. The company works in partnership with Denali Therapeutics Inc, Merck KGaA and Takeda Pharmaceutical Company Limited. It operates in the UK and the US. F-star Therapeutics is headquartered in Cambridge, England, the UK.
For a complete picture of FS-102’s drug-specific PTSR and LoA scores, buy the report here.