Geron. has filed a patent for the synthesis of orthogonally protected 3′-amino nucleoside monomers. The method involves selectively protecting the 3′-amino group while leaving the nucleoside base unprotected. Claim 1 details the process for preparing adenosine, guanosine, or cytidine monomers with protected nucleoside bases and 3′-amino groups. GlobalData’s report on Geron gives a 360-degree view of the company including its patenting strategy. Buy the report here.

Smarter leaders trust GlobalData


Data Insights Geron Corp - Company Profile

Buy the Report

Data Insights

The gold standard of business intelligence.

Find out more

According to GlobalData’s company profile on Geron, Peptide pharmacophores was a key innovation area identified from patents. Geron's grant share as of January 2024 was 48%. Grant share is based on the ratio of number of grants to total number of patents.

Method for synthesizing orthogonally protected 3'-amino nucleoside monomers

Source: United States Patent and Trademark Office (USPTO). Credit: Geron Corp

A recently filed patent (Publication Number: US20240034748A1) describes a method for preparing adenosine, guanosine, or cytidine monomers with protected nucleoside bases and 3'-amino groups. The method involves providing a monomer with an unprotected 3'-amino-3'-deoxy base, selectively reacting the 3'-amino group with a protecting group, reacting the 5'-hydroxyl group with another protecting group, and reacting the nucleoside base with a third protecting group. Importantly, the protecting groups can be selectively removed without affecting the other protected groups, allowing for precise control over the deprotection process.

The patent also includes a series of canceled claims, indicating a focus on the specific method outlined in claim 1 for preparing nucleoside monomers with protected bases and 3'-amino groups. This method could have significant implications for the synthesis of nucleoside analogs and other compounds where precise protection and deprotection steps are crucial. By providing a detailed and controlled approach to protecting nucleoside bases and 3'-amino groups, this patent may offer a valuable tool for researchers and industry professionals working in the field of nucleoside chemistry.

To know more about GlobalData’s detailed insights on Geron, buy the report here.

Data Insights


The gold standard of business intelligence.

Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors.


GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies