The Glutamate Receptor Ionotropic NMDA 2B pipeline drugs market research report outlays comprehensive information on the Glutamate Receptor Ionotropic NMDA 2B targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Glutamate Receptor Ionotropic NMDA 2B pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
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The report also covers products from therapy areas such as Central Nervous System, Cardiovascular, Respiratory, and Dermatology which include the indications Post-Traumatic Stress Disorder (PTSD), Neurodegenerative Diseases, Cardiac Arrest, Orthostatic Hypotension, Idiopathic Pulmonary Fibrosis, Chronic Cough, and Burns. It also reviews key players involved in Glutamate Receptor Ionotropic NMDA 2B targeted therapeutics development with respective active and dormant or discontinued products.
The Glutamate Receptor Ionotropic NMDA 2B pipeline targets constitutes close to 15 molecules. Out of which, approximately 14 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase II, Phase I, Preclinical, and Discovery stages are 1, 3, 3, 6, and 1 respectively. Similarly, the universities portfolio in Preclinical comprises 1 molecule.
Glutamate Receptor Ionotropic NMDA 2B overview
Glutamate receptor subunit epsilon-2 or N-methyl D-aspartate receptor subtype 2B (NMDAR2B or NR2B) is a protein encoded by the GRIN2B gene. It is mediated by glycine. It acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them resulting in an irreversible neuronal death.
For a complete picture of Glutamate Receptor Ionotropic NMDA 2B’s drug pipeline, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third-party sources.
Drug profiles featured in the report undergo periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.
