Golcadomide is a small molecule commercialized by Bristol-Myers Squibb, with a leading Phase III program in Diffuse Large B-Cell Lymphoma. According to Globaldata, it is involved in 14 clinical trials, of which 3 were completed, 9 are ongoing, and 2 are planned. GlobalData uses proprietary data and analytics to provide a complete picture of Golcadomides valuation in its risk-adjusted NPV model (rNPV). Buy the model here.
The revenue for Golcadomide is expected to reach an annual total of $45 mn by 2036 in the US based off GlobalDatas Expiry Model. The drugs revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV). Applying the drugs phase transition success rate to remaining R&D costs and likelihood of approval (LoA) to sales related costs provides a risk-adjusted NPV model (rNPV). The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress.
Golcadomide Overview
Golcadomide hydrochloride (CC-99282) is under development for the treatment of relapsed or refractory, non-Hodgkin lymphoma, diffuse large B cell lymphoma, primary mediastinal B-cell lymphoma, marginal zone b-cell lymphoma, unspecified B-cell lymphomas, follicular lymphoma, relapsed or refractory chronic lymphocytic leukemia (small lymphocytic lymphoma) and T-cell lymphomas. The drug candidate is administered by oral route and is a next-generation molecular glue CELMoD compound (cereblon E3 ligase modulation drugs) which acts by targeting cereblon protein.
Bristol-Myers Squibb Overview
Bristol-Myers Squibb (BMS) is a specialty biopharmaceutical company that is engaged in discovery, development, licensing and manufacturing, marketing, distribution and sale of medicines and related medical products to patients with serious diseases. Its primary focus is on cancer, immunology, cardiovascular, and fibrotic therapeutic projects. The company offers its products across the world to wholesalers, retail pharmacies, medical professionals, hospitals and government entities. BMS provides its products in the US, Europe, and Japan. The company conducts research to focus on the discovery and development of novel medicines that address serious diseases in areas of significant unmet medical need. BMS is headquartered in Princeton, New Jersey, the US.
The company reported revenues of (US Dollars) US$45,006 million for the fiscal year ended December 2023 (FY2023), a decrease of 2.5% over FY2022. In FY2023, the companys operating margin was 20.9%, compared to an operating margin of 20.9% in FY2022. In FY2023, the company recorded a net margin of 17.8%, compared to a net margin of 13.7% in FY2022.
The company reported revenues of US$11,865 million for the first quarter ended March 2024, an increase of 3.4% over the previous quarter.
For a complete picture of Golcadomides valuation, buy the drugs risk-adjusted NPV model (rNPV) here.
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