Golidocitinib is under clinical development by Dizal Pharmaceutical and currently in Phase II for Peripheral T-Cell Lymphomas (PTCL). According to GlobalData, Phase II drugs for Peripheral T-Cell Lymphomas (PTCL) have a 29% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how Golidocitinib’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Golidocitinib overview

Golidocitinib (DZD-4205) is under development for the treatment of non-small cell lung cancer and T cell lymphomas including peripheral T cell lymphoma, vascular immunoblast type (AITL), Anaplastic large cell type-ALK positive (ALCL ALK+), anaplastic large cell type-ALK negative (ALCL ALK-); enteropathy-associated T cell lymphoma (EATL), monomorphic epithelial intestinal T cell lymph Tumor (MEITL), NK/T cell lymphoma (NKTCL), liver 44 splenic T cell lymphoma (HSTCL), subcutaneous panniculitis-like T cell lymphoma (SPTCL), relapsed and refractory cutaneous T-cell lymphomas including granuloma fungoides (MF) or Sezary syndrome (SS) It is a small molecule which acts by targeting JAK 1. It is administered through oral route in the form of capsules.

Dizal Pharmaceutical overview

Dizal Pharmaceutical (Dizal) is a biopharmaceutical company. It focuses on research, development, and commercialization of therapies to treat cancer and immunological diseases. The company’s lead product candidate ZEGFROVY, which is at marketing approval stage for treatment of solid tumors. Its product pipeline includes other drug programs such as JAUKPO to treat hematological malignancy, solid tumors, and immunological diseases; DZD8586 for treatment of hematological malignancy; and DZD2269 and DZD1516 to treat solid tumors. The company operates with additional facilities in Beijing, Wuxi, Chengdu, China. Dizal is headquartered in Shanghai, China.

For a complete picture of Golidocitinib’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 7 February 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.