GSBR-1290 is under clinical development by Structure Therapeutics and currently in Phase II for Obesity. According to GlobalData, Phase II drugs for Obesity have a 29% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how GSBR-1290’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

GSBR-1290 overview

GSBR-1290 is under development for the treatment of type 2 diabetes and obesity. It is administered through oral route as capsules or tablets. The therapeutic candidate acts as glucagon-like peptide-1 (GLP1) receptor agonist. It is developed based on the Schrodinger artificial intelligence (AI) technology.

Structure Therapeutics overview

Structure Therapeutics is a clinical-stage biopharmaceutical company. It discovers and develops novel oral therapies for chronic metabolic and pulmonary diseases. The company utilizes its structure-based technology platform that combines direct visualization of receptor-binding interactions with advanced simulation of molecular motion and signal transduction. Structure Therapeutics’ pipeline includes GSBR-1290 to treat obesity, cardiovascular, and metabolic diseases; ANPA-0073 for the treatment of selective weight loss obesity; and LTSE-2578 to treat pulmonary diseases. The company operates in China and the US. Structure Therapeutics is headquartered in South San Francisco, California, the US.

For a complete picture of GSBR-1290’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 12 April 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.