Harrow Health has been granted a patent for formulations and compositions targeting ocular diseases like dry eye disease. The patent includes a preservative-free ophthalmic composition stored in a dropper bottle, containing specific ingredients like povidone, polyvinyl alcohol, and more. GlobalData’s report on Harrow Health gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Harrow Health, Peptide pharmacophores was a key innovation area identified from patents. Harrow Health's grant share as of February 2024 was 31%. Grant share is based on the ratio of number of grants to total number of patents.

Preservative-free ophthalmic composition for dry eye disease

Source: United States Patent and Trademark Office (USPTO). Credit: Harrow Health Inc

A recently granted patent (Publication Number: US11918603B2) discloses a unique ophthalmic composition stored in a dropper bottle. The composition is preservative-free and includes a combination of ingredients such as povidone, fully hydrolyzed polyvinyl alcohol, partially hydrolyzed polyvinyl alcohol, sodium chloride, boric acid, disodium edetate dihydrate, potassium chloride, glycerin, ethyl alcohol, lecithin, polysorbate 80, a pH adjusting agent, and water. The molecular weight of the fully hydrolyzed polyvinyl alcohol falls within the range of 20,000 to 200,000 daltons, ensuring its efficacy within the formulation.

Moreover, the patent outlines specific concentrations for each ingredient, ranging from povidone to polysorbate 80, to maintain the composition's stability and effectiveness. The pH of the composition is regulated to not exceed 6.6, while the osmolality falls between 200 mOsm/kg to 400 mOsm/kg. The dropper bottle housing the composition is designed with a squeezable container and a tapered dispenser ending in a discharge aperture, facilitating precise application. With a volume of 10 mL, the dropper bottle ensures convenient and controlled dispensing of the ophthalmic solution, catering to user-friendly application and storage needs.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies