HCA Healthcare has been granted a patent for a cassette that prepares imaging agents. The cassette includes a linear arrangement of stopcock manifolds, including an ethanol reservoir, a syringe with ascorbic acid or salt solution, a syringe with water, and a final product vial. The invention allows for the synthesis and use of imaging agents for various areas of interest in the body. GlobalData’s report on HCA Healthcare gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on HCA Healthcare, Cloud gaming was a key innovation area identified from patents. HCA Healthcare's grant share as of September 2023 was 73%. Grant share is based on the ratio of number of grants to total number of patents.

Cassette for preparing imaging agent

Source: United States Patent and Trademark Office (USPTO). Credit: HCA Healthcare Inc

A recently granted patent (Publication Number: US11744906B2) describes a cassette and apparatus for the preparation of an imaging agent. The cassette consists of a linear arrangement of stopcock manifolds, with different configurations outlined in the claims. The first claim describes a cassette with a linear arrangement of stopcock manifolds that includes an ethanol reservoir, a syringe with a solution of ascorbic acid or its salt, a syringe with water, and a final product vial.

The subsequent claims provide variations of the cassette design, with additional components and different orders of arrangement. These variations include the inclusion of luer connections for gas inlet and [18O]H2O recovery, anion exchange cartridges, spike connections for acetonitrile, empty syringes, reservoirs with imaging agent precursors, reaction vessels, outlets to HPLC, and inlets from HPLC. Some claims also mention the presence of stabilizing agents and the capability of preparing imaging agents of specific formulas.

The apparatus described in the patent follows a similar linear arrangement of stopcock manifolds as the cassette. It includes an ethanol reservoir, a final product vial, a syringe with water, and a syringe with a solution of ascorbic acid or its salt. Like the cassette, the apparatus also has variations in its design, with additional components and different orders of arrangement. These variations include luer connections for gas inlet and [18O]H2O recovery, anion exchange cartridges, spike connections for acetonitrile, empty syringes, reservoirs with imaging agent precursors, reaction vessels, outlets to HPLC, and inlets from HPLC.

Overall, the patent describes a cassette and apparatus for the preparation of an imaging agent. The linear arrangement of stopcock manifolds allows for the sequential flow of different solutions and reagents, facilitating the synthesis of the imaging agent. The variations in the cassette and apparatus design provide flexibility in accommodating different components and processes involved in the preparation of the imaging agent.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies