The Histone Deacetylase 1 pipeline drugs market research report outlays comprehensive information on the Histone Deacetylase 1 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Histone Deacetylase 1 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Oncology, Central Nervous System, Genetic Disorders, and Immunology which include the indications Breast Cancer, Solid Tumor, Parkinson’s Disease, Huntington Disease, Duchenne Muscular Dystrophy, Becker Muscular Dystrophy, and Systemic Lupus Erythematosus. It also reviews key players involved in Histone Deacetylase 1 targeted therapeutics development with respective active and dormant or discontinued products.
The Histone Deacetylase 1 pipeline targets constitutes close to 32 molecules. Out of which, approximately 24 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Pre-Registration, Phase II, Phase I, IND/ CTA Filed, and Preclinical stages are 3, 8, 1, 1, and 11 respectively. Similarly, the universities portfolio in Preclinical, and Discovery comprises 7, and 1 molecule.
Histone Deacetylase 1 overview
Histone deacetylase 1 is an enzyme encoded by the HDAC1 gene. The protein encoded by this gene belongs to the histone deacetylase family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2 MTA2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. It plays an important role in transcriptional regulation, cell cycle progression and developmental events.
For a complete picture of Histone Deacetylase 1’s drug pipeline, buy the report here.
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