HU Group. has been granted a patent for a method to measure lectin-binding substances in samples. The process involves capturing the substance using a specialized carrier, washing away contaminants, releasing the substance, and measuring it with a lectin, ensuring accurate purification and analysis. GlobalData’s report on HU Group gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on HU Group, was a key innovation area identified from patents. HU Group's grant share as of June 2024 was 47%. Grant share is based on the ratio of number of grants to total number of patents.
The granted patent US12038440B2 outlines a method for measuring lectin-binding substances in a sample, which involves a systematic purification process. This method includes three key steps: a capturing step, a washing step, and a releasing step. In the capturing step, a capture carrier, which consists of a water-insoluble carrier and an immobilized molecule capable of binding to the lectin-binding substance, is brought into contact with the sample. This interaction allows the capture carrier to isolate the lectin-binding substance. Following this, the washing step removes any unbound contaminants, and the releasing step extracts the purified lectin-binding substance from the capture carrier, resulting in a prepared sample for measurement.
The measurement of the purified lectin-binding substance is conducted using a lectin, which can be either a labeled lectin or a blocked labeled lectin. The patent specifies that the lectin-binding substance must possess a glycan that can bind to the lectin, while the capturing molecule recognizes and binds to a non-glycan portion of the lectin-binding substance. Additionally, the method allows for the measurement to occur in the presence of a free second water-soluble polymer, enhancing the versatility of the measurement process. Overall, this patent presents a detailed and structured approach to accurately measuring lectin-binding substances, which could have significant applications in biochemical research and diagnostics.
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