The Hypocretin Receptor pipeline drugs market research report outlays comprehensive information on the Hypocretin Receptor targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Hypocretin Receptor pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Central Nervous System, Respiratory, Metabolic Disorders, and Toxicology which include the indications Narcolepsy, Idiopathic Hypersomnia (IH), Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease (COPD), Obesity, and Opioid Induced Side Effects. It also reviews key players involved in Hypocretin Receptor targeted therapeutics development with respective active and dormant or discontinued products.
The Hypocretin Receptor pipeline targets constitutes close to 36 molecules. Out of which, approximately 35 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Pre-Registration, Phase III, Phase II, Phase I, Preclinical, and Discovery stages are 2, 5, 7, 5, 5, and 11 respectively. Similarly, the universities portfolio in Preclinical comprises 1 molecule.
Hypocretin Receptor overview
The hypocretin receptor, also known as the orexin receptor, is a G-protein-coupled receptor that binds to the neuropeptide orexin. There are two variants of the receptor, OX1 and OX2, each encoded by a different gene. The orexin system consists of two neuropeptides, orexin-A/hypocretin-1 and orexin-B/hypocretin-2. The orexins bind to and activate two G-protein–coupled receptors (GPCRs), orexin receptor type 1 (OX1R) and type 2 (OX2R). The hypocretin type 1 receptor binds only to hypocretin-1, while the hypocretin type 2 receptor can bind to both type 1 and type 2 ligands.
For a complete picture of Hypocretin Receptor’s drug pipeline, buy the report here.
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