IBI-110 is under clinical development by Innovent Biologics and currently in Phase II for Hepatocellular Carcinoma. According to GlobalData, Phase II drugs for Hepatocellular Carcinoma have a 33% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how IBI-110’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
IBI-110 is under development for the treatment of refractory solid tumors, advanced head and neck squamous cell carcinoma, oral cavity, oropharyngeal, laryngeal and hypopharyngeal cancer, squamous non-small cell lung cancer, gastric cancer, non-small cell lung cancer, adenocarcinoma of the gastroesophageal junction, small-cell lung cancer, lymphoma and hepatocellular carcinoma (HCC) and esophageal squamous cell carcinoma. The drug candidate is administered by intravenous drip route and acts by targeting lymphocyte activation gene 3 protein (LAG3).
It was also under development for the treatment of metastatic cutaneous melanoma and diffuse large B-cell lymphoma.
Innovent Biologics overview
Innovent Biologics is a biopharmaceutical company that carries out the research, development and manufacturing of monoclonal antibodies. It provides products for various diseases such as metabolic, cancer, autoimmune diseases and other therapeutic areas. The company’s oncology products include sintilimab injection, bevacizumab injection, rituximab injection, pemigatinib, olverembatinib, ramucirumab, and others. Its autoimmune drugs are adalimumab injection, IBI-353, IBI-112 and IBI-314, among others. The company’s metabolic and ophthalmology products include IBI-306, IBI-362, IBI-302, IBI-324, IBI-311
For a complete picture of IBI-110’s drug-specific PTSR and LoA scores, buy the report here.