Iguratimod is a Small Molecule owned by Simcere Pharmaceutical Group, and is involved in 8 clinical trials, of which 4 were completed, 3 are ongoing, and 1 is planned.
Iguratimod inhibits the activity of nuclear factor- kappaB (NF-kappaB), thereby inhibiting the generation of inflammatory cytokines (interleukin -1, interleukin-6, interleukin-8, and a tumor necrosis factor). The proinflammatory cytokines, mainly TNF-a, IL-1beta and IL-6, are considered powerful targets in the treatment of rheumatoid arthritis.
The revenue for Iguratimod is expected to reach a total of $1.7bn through 2038. This change impacts the valuation of this asset and is an important factor to understand the current value of the drug in a clinical process. View the complete picture with the Iguratimod NPV Report.
Iguratimod is currently owned by Simcere Pharmaceutical Group.
Iguratimod (Iremod) is a methane-sulfonanilide derivative acts as disease- modifying anti-rheumatic agent. It is formulated as tablets for oral route of administration. It is indicated for the treatment of hand osteoarthritis and Immune Thrombocytopenic Purpura.
Iguratimod is under development for the treatment of primary Sjogren's syndrome in China. It is administered through oral route as tablet.
Simcere Pharmaceutical Group Overview
Simcere Pharmaceutical Group (Simcere) is a pharmaceutical company discovers, develops, and markets branded generic and prescription pharmaceutical products. The company offers products in therapeutic areas such as anti-tumor, anti-infection, central nervous, cardiovascular, skeletal muscle, and others. Its product portfolio includes recombinant human endostatin injection, palonosetron hydrochloride injection, nedaplatin for injection, fluorouracil implants and lyvamlodipine besylate tablets, among others. Simcere’s products are used for the treatment of oncology, infectious diseases, neurology, anti-inflammation and also cardiovascular diseases. The company conducts research and development focused on low end generics and APIs to innovative medicines. The company’s precision medicine sector, Simcere diagnostics had strategic partnership t with Agena bioscience focused on Agena’s Massarray System for companion diagnostics and pharmacogenetic testing in China. Simcere is headquartered in Nanjing, Jiangsu, China
The company reported revenues of (Renminbi) CNY4,999.7 million for the fiscal year ended December 2021 (FY2021), an increase of 10.9% over FY2020. In FY2021, the company’s operating margin was 29%, compared to an operating margin of 20.6% in FY2020. In FY2021, the company recorded a net margin of 30.1%, compared to a net margin of 14.8% in FY2020.
Quick View – Iguratimod
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