The pharmaceutical industry continues to be a hotbed of patent innovation. Activity is driven by the evolution of treatment paradigms, and the gravity of unmet needs, as well as the growing importance of technologies such as pharmacogenomics, digital therapeutics, and artificial intelligence. In the last three years alone, there have been over 787,000 patents filed and granted in the pharmaceutical industry, according to GlobalData’s report on Cell & gene therapy in pharma: pancreatic cell transplantationBuy the report here.

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According to GlobalData’s Technology Foresights, which uses over 668,000 patents to analyze innovation intensity for the pharmaceutical industry, there are 80+ innovation areas that will shape the future of the industry.

Pancreatic cell transplantation is a key innovation area in cell & gene therapy

Pancreatic cell transplantation is a medical procedure in which cells from the pancreas of a donor are transplanted into the pancreas of a recipient. The procedure’s goal is to replace damaged or nonfunctioning pancreatic cells in individuals with diabetes so that they can produce insulin and regulate their blood sugar levels more effectively.

GlobalData’s analysis also uncovers the companies at the forefront of each innovation area and assesses the potential reach and impact of their patenting activity across different applications and geographies. According to GlobalData, there are 100+ companies, spanning technology vendors, established pharmaceutical companies, and up-and-coming start-ups engaged in the development and application of pancreatic cell transplantation.

Key players in pancreatic cell transplantation – a disruptive innovation in the pharmaceutical industry

‘Application diversity’ measures the number of applications identified for each patent. It broadly splits companies into either ‘niche’ or ‘diversified’ innovators.   

‘Geographic reach’ refers to the number of countries each patent is registered in. It reflects the breadth of geographic application intended, ranging from ‘global’ to ‘local’.  

Patent volumes related to pancreatic cell transplantation

Company Total patents (2010 - 2022) Premium intelligence on the world's largest companies
ViaCyte 148 Unlock Company Profile
Johnson & Johnson 110 Unlock Company Profile
East-West Capital Partners 63 Unlock Company Profile
Astellas Pharma 49 Unlock Company Profile
Children's Medical Center 48 Unlock Company Profile
Takeda Pharmaceutical 43 Unlock Company Profile
Orgenesis 42 Unlock Company Profile
Tel Hashomer Medical Research Infrastructure and Services 38 Unlock Company Profile
Boston Children's Hospital 29 Unlock Company Profile
Accelerated Biosciences 28 Unlock Company Profile
United Therapeutics 28 Unlock Company Profile
PT Soho Global Health 28 Unlock Company Profile
Daiichi Sankyo 27 Unlock Company Profile
Mesoblast 27 Unlock Company Profile
SymbioCellTech 27 Unlock Company Profile
BioCrine 25 Unlock Company Profile
Massachusetts General Hospital 25 Unlock Company Profile
Vertex Pharmaceuticals 24 Unlock Company Profile
Shin-Etsu Chemical 23 Unlock Company Profile
InCube Labs 23 Unlock Company Profile
Otsuka 21 Unlock Company Profile
CRISPR Therapeutics 21 Unlock Company Profile
Defymed 18 Unlock Company Profile
Protokinetix 17 Unlock Company Profile
Beta Cell Technologies 16 Unlock Company Profile
Tristem Trading (Cyprus) 16 Unlock Company Profile
Allele Biotechnology and Pharmaceuticals 16 Unlock Company Profile
International Stem Cell 16 Unlock Company Profile
Beta-Cell 14 Unlock Company Profile
Eidgenossische Technische Hochschule Zurich 13 Unlock Company Profile
Kadimastem 12 Unlock Company Profile
Orizuru Therapeutics 12 Unlock Company Profile
Bioactive Regenerative Therapeutics 12 Unlock Company Profile
Biogen 12 Unlock Company Profile
eGenesis 11 Unlock Company Profile
Platinum Equity 11 Unlock Company Profile
General Hospital 10 Unlock Company Profile
Athersys 10 Unlock Company Profile
AAL Scientifics 9 Unlock Company Profile
Hangzhou Qihan Biotechnology 9 Unlock Company Profile
MB Pharma Sro 9 Unlock Company Profile
Geron 8 Unlock Company Profile
Isla Technologies 7 Unlock Company Profile
The New York Stem Cell Foundation 7 Unlock Company Profile
Apollo Endosurgery 7 Unlock Company Profile
Lifescan 6 Unlock Company Profile
Australian Foundation For Diabetes Research 6 Unlock Company Profile
Centre National de la Recherche Scientifique 6 Unlock Company Profile
Elixirgen 6 Unlock Company Profile
AstraZeneca 6 Unlock Company Profile

Source: GlobalData Patent Analytics

ViaCyte, formerly Novocell, is one of the leading patent filers in pancreatic cell transplantation. It is a regenerative medicine company developing novel cell replacement therapies for the treatment of diabetes to achieve glucose control targets and reduce the risk of hypoglycemia and diabetes-related complications. Its pipeline product candidates include PEC-Direct (VC-02), which delivers stem cell-derived PEC-01 pancreatic progenitor cells in a non-immunoprotective device to allow direct vascularization of the cells for treating type 1 diabetes patients, and PEC-Encap (VC-01), which delivers stem cell-derived pancreatic progenitor cells in the Encaptra immunoprotective device for all insulin-requiring diabetes, Type 1 and Type 2 patients. Johnson & Johnson and Astellas Pharma are some of the other key patent filers in pancreatic cell transplantation.

In terms of application diversity, Allele Biotechnology and Pharmaceuticals leads the pack, while Geron and United Therapeutics stood in second and third positions, respectively. By means of geographic reach, ViaCyte held the top position, followed by United Therapeutics and Accelerated Biosciences.

To further understand the key themes and technologies disrupting the pharmaceutical industry, access GlobalData’s latest thematic research report on Pharmaceutical.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Patent Analytics tracks patent filings and grants from official offices around the world. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.