The Insulin Receptor pipeline drugs market research report outlays comprehensive information on the Insulin Receptor targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Insulin Receptor pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Metabolic Disorders, Oncology, Ophthalmology, and Central Nervous System which include the indications Type 2 Diabetes, Type 1 Diabetes (Juvenile Diabetes), Solid Tumor, Breast Cancer, Graves’ Ophthalmopathy, Retinal Vein Occlusion, Alzheimer’s Disease, and Parkinson’s Disease. It also reviews key players involved in Insulin Receptor targeted therapeutics development with respective active and dormant or discontinued products.
The Insulin Receptor pipeline targets constitutes close to 190 molecules. Out of which, approximately 169 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Pre-Registration, Filing rejected/ Withdrawn, Phase III, Phase II, Phase I, IND/ CTA Filed, Preclinical, and Discovery stages are 14, 2, 28, 21, 23, 9, 51, and 8 respectively. Similarly, the universities portfolio in Phase II, Phase I, Preclinical, and Discovery comprises 1, 1, 16, and 3 molecule.
Insulin Receptor overview
The insulin receptor (IR) is a transmembrane receptor that plays a key role in regulating glucose homeostasis and cell growth and differentiation. It is a heterotetrameric glycoprotein composed of two extracellular α-subunits and two transmembrane β-subunits. The α-subunits bind insulin, while the β-subunits have intrinsic tyrosine kinase activity. Upon insulin binding, the IR undergoes autophosphorylation of its tyrosine residues and activates a cascade of intracellular signaling pathways. These pathways ultimately lead to the uptake of glucose into cells, the suppression of glucose production by the liver, and the stimulation of protein and glycogen synthesis.
For a complete picture of Insulin Receptor’s drug pipeline, buy the report here.
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