The Integrin Alpha 4 pipeline drugs market research report outlays comprehensive information on the Integrin Alpha 4 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Integrin Alpha 4 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Gastrointestinal, Central Nervous System, Immunology, and Musculoskeletal Disorders which include the indications Ulcerative Colitis, Inflammatory Bowel Disease, Relapsing Remitting Multiple Sclerosis (RRMS), Relapsing Multiple Sclerosis (RMS), Graft Versus Host Disease (GVHD), Inflammation, Osteoporosis, and Osteonecrosis. It also reviews key players involved in Integrin Alpha 4 targeted therapeutics development with respective active and dormant or discontinued products.
The Integrin Alpha 4 pipeline targets constitutes close to 25 molecules. Out of which, approximately 25 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Filing rejected/ Withdrawn, Phase III, Phase II, Phase I, IND/ CTA Filed, Preclinical, and Discovery stages are 1, 3, 5, 6, 1, 5, and 4 respectively.
Integrin Alpha 4 overview
Integrin Alpha 4 is a protein encoded by ITGA4. Integrins alpha-4 (VLA-4) subunit associates with a beta 1 or beta-7 subunit to form an integrin that plays a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn’s disease and inflammatory bowel disease. They are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1.
For a complete picture of Integrin Alpha 4’s drug pipeline, buy the report here.
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