IO-202 is under clinical development by Immune Onc Therapeutics and currently in Phase I for Chronic Myelomonocytic Leukemia (CMML). According to GlobalData, Phase I drugs for Chronic Myelomonocytic Leukemia (CMML) have an 82% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how IO-202’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

IO-202 overview

IO-202 is under development for the treatment of relapsed or refractory acute myeloid leukemia, chronic myelomonocytic leukemia, solid tumors, systemic lupus erythematosus and other inflammatory diseases. The drug candidate acts by targeting LILRB4. It is administered through intravenous route.

Immune Onc Therapeutics overview

Immune Onc Therapeutics (Immune-Onc) is a cancer immunotherapy company. It discovers and develops new immunomodulatory approaches to treat immunology and inflammation, blood cancers, and solid tumors. The company aims to translate unique scientific insights into the immune suppressive pathways and tumor microenvironment to develop first-in-class biotherapeutics. Immune-Onc develops a novel class of antibodies that modulate or deplete specific subsets of myeloid cells involved in disease pathogenesis. It identifies and utilizes antibodies targeting an immune inhibitory receptor for the treatment of acute myeloid leukemia (AML) and other cancers. Its pipeline product includes IO-202, for acute myeloid leukemia and other hematologic and solid tumors. Immune-Onc is headquartered in Palo Alto, California, the US.

For a complete picture of IO-202’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 18 March 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.