Magrolimab is under clinical development by Gilead Sciences and currently in Phase II for Oropharyngeal Cancer. According to GlobalData, Phase II drugs for Oropharyngeal Cancer have a 50% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how Magrolimab’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Magrolimab overview
Magrolimab is under development for the treatment of solid tumor, relapsed/refractory multiple myeloma, oral cavity cancer, oropharyngeal cancer, hypopharyngeal cancer, laryngeal cancer, pancreatic ductal adenocarcinoma, urethral cancer, ureter cancer, breast cancer, colorectal cancer, epithelial ovarian cancer, fallopian tube cancer, peritoneal cancer, head and neck cancer, ovarian, indolent lymphoma, metastatic transitional (urothelial) tract cancer, bladder cancer, and atherosclerosis. It is a humanized IgG4 subclass monoclonal antibody. The drug candidate is administered through intravenous route. It acts by targeting CD47.
It was also under development for metastatic small cell lung cancer and metastatic non-small cell lung cancer, metastatic colorectal cancer, recurrent head and neck squamous cell carcinoma, triple negative breast cancer, cutaneous T-cell lymphoma, Hodgkin lymphoma., previously untreated, relapsed or refractory acute myelocytic leukemia, NHL, myelodysplastic syndrome, relapsed and refractory B-cell non-Hodgkin's lymphoma, diffuse large B-cell lymphoma, ependymoma, marginal zone or follicular lymphoma.
Gilead Sciences overview
Gilead Sciences (Gilead) is a research-based biopharmaceutical company. It carries out the discovery, development and commercialization of medicines for the treatment of cardiovascular, hematological and respiratory diseases, inflammation, liver diseases such as hepatitis B virus (HBV) and hepatitis C virus (HCV) infections, cancer, and human immunodeficiency virus (HIV) infection. It markets its products through commercial teams, third-party distributors and corporate partners. Gilead’s commercial teams promote its products through direct field contact with physicians, hospitals, clinics and other healthcare providers. The company sells its products through subsidiaries and distributors in Europe, the Americas, Asia-Pacific, the Middle East, and Africa. Gilead is headquartered in Foster City, California, the US.
For a complete picture of Magrolimab’s drug-specific PTSR and LoA scores, buy the report here.
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