(MG-010 + sorafenib) is under clinical development by Metagone Biotech and currently in Phase II for Hepatocellular Carcinoma. According to GlobalData, Phase II drugs for Hepatocellular Carcinoma have a 33% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how (MG-010 + sorafenib)’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

(MG-010 + sorafenib) overview

A fixed dose combination (MGD-1609) of MG-010 and sorafenib is under development for the treatment of solid tumors including gastric cancer, non-small cell lung carcinoma, renal cell carcinoma, colorectal cancer and hepatocellular carcinoma. Sorafenib acts by targeting protein kinase VEGFR1, VEGFR2, VEGFR3, RET, c-kit, FLT3, PDGFRB and MG-010 acts by targeting proto-oncogene c RAF (RAF1). It is administered through oral route.

For a complete picture of (MG-010 + sorafenib)’s drug-specific PTSR and LoA scores, buy the report here.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.