MVXONCO-1 is under clinical development by Release Therapeutics and currently in Phase II for Pharyngeal Neoplasm. According to GlobalData, Phase II drugs for Pharyngeal Neoplasm have a 44% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how MVXONCO-1’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

Smarter leaders trust GlobalData

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

MVXONCO-1 overview

MVXONCO-1 is under development for the treatment of lung carcinoma (either small cell or non-small cell), colon, breast, pancreas (exocrine or endocrine), stomach, oesophagus, head and neck squamous cell carcinoma, thyroid, kidney, bladder, prostate, ovary, uterus (cervix or corpus), sarcoma of soft tissue, bone, uterus, melanoma, chordoma, oral cavity cancer, pharyngeal cancer, laryngeal cancer and primary brain tumor. The drug candidate is a personalized vaccine administered subcutaneously as injections and capsules implantations. The drug candidate is a combination of two components, MVX-1-loaded microcapsules and irradiated autologous tumor cells.

Release Therapeutics overview

Release Therapeutics (Release), formerly MaxiVAX, is a biotechnology company that develops active immunotherapy with encapsulated cells for the treatment of cancer. Its lead product candidate includes MVX-ONCO-1, an immuno-oncology therapeutic vaccination that activates the patient’s own natural immune response mechanism through innovative and proprietary technology in order to eliminate the deadly cancer cells. The company also conducts Phase 2 clinical study for the treatment of head and neck cancer and several solid tumors. Release is headquartered in Geneva, Switzerland.

For a complete picture of MVXONCO-1’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 20 February 2024

Data Insights

From

The gold standard of business intelligence.

Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors.

GlobalData

GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.