MWTx-01 is under clinical development by Disc Medicine and currently in Phase I for Beta Thalassaemia. According to GlobalData, Phase I drugs for Beta Thalassaemia have an 89% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how MWTx-01’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
MWTx-01 overview
MWTx-01 is under development for the treatment of beta-thalassemia and Polycythemia Vera. The therapeutic candidate is a humanized monoclonal antibody that is administered through intravenous or subcutaneous route. It acts by targeting transmembrane protease serine 6 (TMPRSS6).
Disc Medicine overview
Disc Medicine, formerly Gemini Therapeutics Inc, is a clinical-stage biopharmaceutical company that specialises in the discovery, development and commercialization of novel treatments for patients with severe hematologic disorders. The company pipeline includes bitopertin for the treatment of erythropoietic porphyrias, including erythropoietic protoporphyria and X-linked protoporphyria and Diamond-Blackfan Anaemia, or DBA; DISC-0974 for the treatment of anaemia of myelofibrosis and anaemia of chronic kidney disease, or CKD; and MWTX-003 for the treatment of polycythemia vera, or PV, and other hematologic disorders. The company’s preclinical programmes consist of DISC-0998, which is used to treat anaemia brought on by inflammatory disorders. Disc Medicine is headquartered in Cambridge, Massachusetts, the US.
For a complete picture of MWTx-01’s drug-specific PTSR and LoA scores, buy the report here.
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