Naporafenib is under clinical development by Erasca and currently in Phase III for Metastatic Melanoma. According to GlobalData, Phase III drugs for Metastatic Melanoma have a 43% phase transition success rate (PTSR) indication benchmark for progressing into Pre-Registration. GlobalData’s report assesses how Naporafenib’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Naporafenib overview

Naporafenib (LXH-254) is under development for the treatment of advanced unresectable or metastatic solid tumor, metastatic melanoma, metastatic colorectal cancer, colon cancer, non small cell lung cancer. The drug candidate is administered orally. It acts by targeting pan RAF kinase. It is a new molecular entity (NME).

Erasca overview

Erasca is an oncology drug development company that uses its artificial intelligence drug discovery platform to treat and cure cancer. The company is headquartered in San Diego, California, the US.

For a complete picture of Naporafenib’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 10 June 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.