The Nitric Oxide Synthase pipeline drugs market research report outlays comprehensive information on the Nitric Oxide Synthase targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Nitric Oxide Synthase pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Central Nervous System, Cardiovascular, Oncology, and Toxicology which include the indications Traumatic Brain Injury, Neurodegenerative Diseases, Thrombosis, Pulmonary Arterial Hypertension, Melanoma, Brain Cancer, Radiation Toxicity (Radiation Sickness, Acute Radiation Syndrome), and Radiation Injury. It also reviews key players involved in Nitric Oxide Synthase targeted therapeutics development with respective active and dormant or discontinued products.
The Nitric Oxide Synthase pipeline targets constitutes close to 21 molecules. Out of which, approximately 14 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase II, Phase I, Preclinical, and Discovery stages are 2, 2, 1, 7, and 2 respectively. Similarly, the universities portfolio in Preclinical, and Discovery comprises 5, and 3 molecule.
Nitric Oxide Synthase overview
Nitric oxide synthase produces nitric oxide (NO). It has three isoforms, which all utilize L-arginine and molecular oxygen as substrates and require the cofactors reduced nicotinamide-adenine-dinucleotide phosphate (NADPH), flavin adenine dinucleotide (FAD), flavin mononucleotide (FMN), and (6R-)5,6,7,8-tetrahydrobiopterin (BH4). All NOS bind calmodulin and contain haem.
For a complete picture of Nitric Oxide Synthase’s drug pipeline, buy the report here.
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