GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Nomacopan overview

Nomacopan is under development for the treatment of uveitis, atopic keratoconjunctivitis (AKC), Guillain-Barre syndrome (GBS), pediatric  and adult hematopoietic stem cell transplant-related thrombotic microangiopathy (HSCT-TMA), trauma, dry age-related macular degeneration (dry-AMD), dry eye and haemorrhagic shock, antiphospholipid syndrome and myasthenia gravis (MG) and lung disease, severe asthma and chronic obstructive pulmonary disease. The therapeutic candidate is a recombinant small protein derived from a protein discovered in the saliva of the Ornithodoros moubata tick. It is administered through subcutaneous, intravitreal and ophthalmic routes. It is also administered through inhalational route as nebulized form. It acts by targeting complement C5 and leukotriene B4 (LTB4). It was also under development for the treatment of paroxysmal nocturnal hemoglobinuria (PNH), COVID-19 pneumonia, bullous pemphigoid (BP), benign mucous membrane pemphigoid, Sjogren's syndrome and atypical hemolytic uremic syndrome (aHUS).

Akari Therapeutics overview

Akari Therapeutics (Akari), formerly Celsus Therapeutics, is a biopharmaceutical company. The company is engaged in the development of therapeutic treatments for rare and orphan autoimmune and inflammatory diseases. It offers coversin drugs that act on complement component-C5 that helps in preventing the release of C5a and formation of C5b – 9. Akari’s pipeline products include paroxysmal nocturnal hemoglobinuria, Guillain Barre Syndrome and atypical hemolytic uremic syndrome. The pipeline products include LTB4+C5, Coversin, Coversin LA, LTB4, LTBA LA, and bioamine inhibitors. It operates its business in Switzerland, Israel, the UK, and the US. Akari is headquartered in London, the UK.

For a complete picture of Nomacopan’s drug-specific PTSR and LoA scores, buy the report here.

Premium Insights

From

The gold standard of business intelligence.

Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors.

Be better informed