OPN-2853 is under clinical development by Opna Bio and currently in Phase II for Solid Tumor. According to GlobalData, Phase II drugs for Solid Tumor have a 10% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how OPN-2853’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

OPN-2853 overview

PLX-2853 is under development for the treatment of myelofibrosis, solid tumors such as small-cell lung cancer, ovarian clear cell carcinoma (OCCC), uveal melanoma, relapsed and refractory acute myeloid leukemia, relapsed and refractory myelodysplastic syndrome, non-Hodgkin lymphoma, diffuse large B-cell lymphoma, follicular lymphoma. The drug candidate is administered through the oral route. The drug candidate acts by targeting bromodomain-containing protein 4.

It was also under development for the treatment of  metastatic castration-resistant prostate cancer (mCRPC), cervical cancer, vaginal cancer, vulvar cancer, uterine cancer, epithelial ovarian cancer, fallopian tube cancer and primary peritoneal cancer..

Opna Bio overview

Opna Bio is a clinical-stage biopharmaceutical company focuses on the development and discovery of novel oncology therapeutics. Opna Bio is headquartered in Vaud, Switzerland.

For a complete picture of OPN-2853’s drug-specific PTSR and LoA scores, buy the report here.

GlobalData

GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in its clinical pathway (PTSR), as well as how likely the drug will be approved (LoA). This is based on a proprietary algorithm built from the drugs’ sales forecast, regulatory milestones, cost forecasts, WACC rate and other proprietary data sources found on GlobalData’s Pharmaceutical Intelligence Center.