ORIC-944 is under clinical development by ORIC Pharmaceuticals and currently in Phase I for Metastatic Castration-Resistant Prostate Cancer (mCRPC). According to GlobalData, Phase I drugs for Metastatic Castration-Resistant Prostate Cancer (mCRPC) have an 88% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how ORIC-944’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

ORIC-944 overview

ORIC-944 is under development for the treatment of metastatic hormone refractory (castration resistant, androgen-independent) prostate cancer and Diffuse Large B cell Lymphoma. The drug candidates is an imidazopyrimidine binder. It acts by targeting EED (polycomb protein EED). It is administered through oral route.

ORIC Pharmaceuticals overview

ORIC Pharmaceuticals is clinical-stage oncology company focused on the discovery and development of novel therapies against treatment-resistant cancers. Its lead drug candidate ORIC-101, is a selective small molecule antagonist of the glucocorticoid receptor (GR), implicated in resistance to various treatment modalities such as chemotherapy, immunotherapy and anti-hormonal therapy across a broad range of cell lines and tumor types. The company is funded by EcoR1 Capital, The Column Group, OrbiMed Advisors, Topspin Partners, Foresite Capital and Kravis Investment Partners. ORIC Pharmaceuticals is headquartered in South San Francisco, California, the US.

For a complete picture of ORIC-944’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 2 September 2023

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.