PF-08046052 is under clinical development by Pfizer and currently in Phase I for Metastatic Colorectal Cancer. According to GlobalData, Phase I drugs for Metastatic Colorectal Cancer have an 84% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how PF-08046052’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
PF-08046052 overview
PF-08046052 (LAVA-1223) is under development for the treatment of solid tumors including non-small cell lung cancer, pancreatic ductal adenocarcinoma, metastatic colorectal cancer and head and neck cancer squamous cell carcinoma. The therapeutic candidate comprises single domain bi-specific antibody that acts by targeting T cell receptor of Vgamma9Vdelta2 T-cells and EGFR. It is administered by parenteral route and is being developed based on bi-specific gamma delta T cell engager (bsTCEs) platform.
Pfizer overview
Pfizer discovers, develops, manufactures, and commercializes biopharmaceuticals. The company offers products to treat various conditions such as cardiovascular, metabolic and pain, women’s health, cancer, inflammation, immune disorders, and rare diseases. It also provides sterile injectable pharmaceuticals, biosimilars, active pharmaceutical ingredients (APIs) and contract manufacturing services. Pfizer sells its products through wholesalers, retailers, hospitals, individual provider offices, clinics, government agencies and pharmacies. It has major manufacturing facilities in India, China, Japan, Ireland, Italy, Belgium, Germany, Singapore, and the US. The company provides its products in North America, South America, Asia-Pacific, Australia, Europe, Africa, and the Middle East. Pfizer is headquartered in New York, the US.
For a complete picture of PF-08046052’s drug-specific PTSR and LoA scores, buy the report here.
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