Pfizer has been granted a patent for compounds that inhibit RET kinase, useful in treating diseases requiring a RET kinase inhibitor. The patent also includes a process for preparing these compounds. GlobalData’s report on Pfizer gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Pfizer, Cancer treatment biomarkers was a key innovation area identified from patents. Pfizer's grant share as of May 2024 was 51%. Grant share is based on the ratio of number of grants to total number of patents.
The granted patent (Publication Number: US11998545B2) discloses a process for preparing compounds of Formula I and Formula 12, involving specific reducing agents and solvents. The process includes steps such as deprotecting compounds of Formula 11a with an amino protecting group like a Boc group, followed by treatment with an acid. The use of reducing agents like NaBH(AcO)3 and solvents such as 1,2-dichloroethane are highlighted in the claims.
Furthermore, the patent claims specify the structural variations allowed in the compounds of Formula I and Formula 12, including the substitution patterns for alkyl, alkoxy, and alkyl groups. The process outlines the specific aldehydes and alkyl groups permissible in the compounds, emphasizing the importance of these structural features in the synthesis. Overall, the patent provides a detailed methodology for the preparation of these compounds, ensuring precision in the selection of reagents and reaction conditions for optimal results.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
