The Poly [ADP Ribose] Polymerase 2 pipeline drugs market research report outlays comprehensive information on the Poly [ADP Ribose] Polymerase 2 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Poly [ADP Ribose] Polymerase 2 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Oncology, Undisclosed, and Cardiovascular which include the indications Ovarian Cancer, Solid Tumor, Unspecified, and Pulmonary Arterial Hypertension. It also reviews key players involved in Poly [ADP Ribose] Polymerase 2 targeted therapeutics development with respective active and dormant or discontinued products.
The Poly [ADP Ribose] Polymerase 2 pipeline targets constitutes close to 26 molecules. Out of which, approximately 25 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Pre-Registration, Phase III, Phase II, Phase I, Preclinical, and Discovery stages are 5, 2, 11, 2, 4, and 1 respectively. Similarly, the universities portfolio in Preclinical comprises 1 molecule.
Poly [ADP Ribose] Polymerase 2 overview
Poly [ADP-ribose] polymerase 2 is an enzyme encoded by the PARP2 gene. It is involved in the base excision repair (BER) pathway, by catalyzing the poly (ADP-ribosylation) of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in signaling pathway leading to the reparation of DNA strand breaks.
For a complete picture of Poly [ADP Ribose] Polymerase 2’s drug pipeline, buy the report here.
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