The Proto Oncogene Tyrosine Protein Kinase ROS pipeline drugs market research report outlays comprehensive information on the Proto Oncogene Tyrosine Protein Kinase ROS targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Proto Oncogene Tyrosine Protein Kinase ROS pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
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The report also covers products from therapy areas such as Oncology, Non Malignant Disorders, Genetic Disorders, and Gastrointestinal which include the indications Non-Small Cell Lung Cancer, Solid Tumor, Vestibular Schwannoma (Acoustic Neuroma), Plexiform Neurofibroma, Neurofibromatoses Type II, and Liver Failure (Hepatic Insufficiency). It also reviews key players involved in Proto Oncogene Tyrosine Protein Kinase ROS targeted therapeutics development with respective active and dormant or discontinued products.
The Proto Oncogene Tyrosine Protein Kinase ROS pipeline targets constitutes close to 28 molecules. Out of which, approximately 27 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Pre-Registration, Phase III, Phase II, Phase I, IND/ CTA Filed, Preclinical, and Discovery stages are 5, 4, 6, 4, 1, 5, and 2 respectively. Similarly, the universities portfolio in Discovery comprises 1 molecule.
Proto Oncogene Tyrosine Protein Kinase ROS overview
Proto-oncogene tyrosine-protein kinase ROS is an enzyme that in humans is encoded by the ROS1 gene. It activates several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. It mediates the phosphorylation of PTPN11, an activator of this pathway. It phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. It mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology.
For a complete picture of Proto Oncogene Tyrosine Protein Kinase ROS’s drug pipeline, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third-party sources.
Drug profiles featured in the report undergo periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.
